CB1R activates the epilepsy-associated protein Go to regulate neurotransmitter release and synaptic plasticity in the cerebellum

Proceedings of the National Academy of Sciences, Volume 121, Issue 49, December 2024.
SignificanceCannabinoid type 1 receptors (CB1Rs) are targets for endocannabinoids and cannabis in the brain and trigger the brain’s reward circuitry. However, it remains elusive how CB1Rs acting as Gi/o-coupled receptors modulate neurotransmitter release …
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